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Biochemistry

Sweat Sodium

Sweat Sodium

Reference Range

Sweat sodium is used as a check of the chloride result. Interpretation is as follows:

Cystic fibrosis unlikely                                  < 50    mmol/L

Supports the diagnosis of CF                         > 90    mmol/L

The Sodium and Chloride concentrations should be within 20 mmol/L of each other.

  • Turnaround Time: 1 day
Sweat Sodium

Sweat Sodium

Reference Range

Sweat sodium is used as a check of the chloride result. Interpretation is as follows:

Cystic fibrosis unlikely                                  < 50    mmol/L

Supports the diagnosis of CF                         > 90    mmol/L

The Sodium and Chloride concentrations should be within 20 mmol/L of each other.

  • Turnaround Time: 1 day
Tacrolimus (FK506 or Prograf)

Tacrolimus (FK506 or Prograf)

Reference Range

Reference or therapeutic ranges are not reported as therapeutic target ranges are applied on an individual basis dependent upon specialty, dosing, period in treatment regime and clinical status. Further advice can be obtained from the appropriate speciality.

  • Turnaround Time: 24 hours
TAU protein (Asialotransferrin) - Query CSF leak

TAU protein (Asialotransferrin) - Query CSF leak

Reference Range

Provided by reference laboratory

  • Turnaround Time: 1 week
Testosterone

Testosterone

Reference Range

Adults (Alinity immunoassay):

Female: <1.9 nmol/L

Male aged 18-49 years: 8.3 - 30.2 nmol/L

Male aged >50 years: 7.7 - 24.8 nmol/L

 

Adults (mass spectrometry):

Female: <1.9 nmol/L

Male: 7.0-27.0 nmol/L

  

Paediatrics:

Group

Testosterone (nmol/L)

Neonates

Not reported (can be elevated during year 1)

Female Tanner 1

<0.6

Male Tanner 1

<0.7

 

Reference for mass spectrometry reference ranges: 

  • Kushnir et al (2010). Liquid Chromatography–Tandem Mass Spectrometry Assay for Androstenedione, Dehydroepiandrosterone, and Testosterone with Pediatric and Adult Reference Intervals. Clinical Chemistry 2010:56;1138–77.
  • Turnaround Time: 24 hours (immunoassay), 5 working days (mass spec)
Theophylline

Theophylline

Reference Range

Therapeutic range: 10-20 mg/L (Pre-dose)

  • Minimum time for patient to reach steady state without loading or after dosage change is 2 days
  • Turnaround Time: 24 hours
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