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Items starting with I

Infectious Mononucleosis Screening Test

Infectious Mononucleosis Screening Test

  • Turnaround Time: 24 hours
Inhibitor Screen

Inhibitor Screen

Reference Range

<12% difference between incubated and immediate mix APTT

  • Turnaround Time: 21 days
IGF-1 (Insulin-like Growth Factor)

IGF-1 (Insulin-like Growth Factor)

Reference Range

Age and gender related reference ranges, please contact laboratory (ext.16543)                                                                                         

 

  • Turnaround Time: 7 days

IGFBP-3 (Insulin-Like Growth Factor Binding Protein-3)

Reference Range

Age and gender specific reference ranges, please contact laboratory

 

  • Turnaround Time: 4 weeks
Insulin

Insulin

Reference Range

No associated reference range. Should be interpreted alongside with glucose and c-peptide.

Non- diabetic hypoglycaemia
Evaluation of hypoglycaemia should only be undertaken for patients in whom Whipple’s triad has been documented. Firstly, review the history and physical findings to exclude more common hypoglycaemic aetiologies such as; drugs (insulin, insulin secretagogues, alcohol ingestion), critical illness (sepsis, organ failure), cortisol deficiency and non-islet cell tumours.
Once these have been excluded, in the seemingly well individual, the differentials lie between accidental/ surreptitious hypoglycaemia and endogenous hyperinsulinaemia. Further evaluation is warranted and should involve the following concomitant tests in the event of an ongoing episode of hypoglycaemia; plasma glucose (for confirmation of hypoglycaemia), insulin, C-peptide, beta-hydroxybutyrate as well as the measurement of circulating oral hypoglycaemic agents (if there is a degree of suspicion). When spontaneous hypoglycaemia cannot be observed, a prolonged fast or mixed meal test may recreate the environment in which hypoglycaemia is likely to occur.

Table 1: Taken from the Endocrine Society Guideline in 2009

Sxs/Signs

Glucose (mmol/L)

Insulin (pmol/L) C-peptide (pmol/L) BHB (mmol/L) Circulating OHA Ab to insulin Interpretation
No <3.1 <21 <200 >2.7 No No Normal
Yes <3.1 >>21 <200 ≤2.7 No Neg (Pos) Exogenous insulin
Yes <3.1 ≥21 ≥200 ≤2.7 No Neg Insulinoma, NIPHS, PGBH
Yes <3.1 ≥21 ≥200 ≤2.7 Yes Neg Oral hypoglycaemic agent
Yes <3.1 >>21 >>200 ≤2.7 No Pos Insulin autoimmune
Yes <3.1 <21 <200 ≤2.7 No Neg IGF mediated
Yes <3.1 <21 <200 >2.7 No Neg Not insulin (or IGF) mediated

 

 

 

 

 

 

 

 

 

 

 

 

 

  • Turnaround Time: 7 days
Iron (Serum)

Iron (Serum)

Reference Range

Male:    11.6 - 31.3 µmol/L

Female:  9.0 - 30.4 µmol/L


The concentration of iron in serum and plasma is dependent upon diet and is subject to circadian variations. Total iron may be slightly lower in the female population.

  • Turnaround Time: 1 day
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