From 1/3/18 renin samples are analysed using the IDS iSYS direct renin mass immunoassay which will use the following reference ranges:
Ambulatory: Female: 6.1 – 62.7 mIU/L, Male: 9.0 – 103 mIU/L
Supine: 4.2 – 59.7 mIU/L
Screen positive for Conns: Aldosterone/renin ratio >91pmol/mU + aldosterone >750 pmol/L
(Endocrine guidelines on the investigation of Conns https://academic.oup.com/jcem/article/93/9/3266/2596343)
The Aldosterone/Renin ratio cut-off that we are providing is a guide only and not a diagnostic test and the ratio should be interpreted, cautiously, in conjunction with relevant clinical information and medications that may affect the ratio.