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Biochemistry

Testosterone

Testosterone

Reference Range

Adults (Alinity immunoassay):

Female: <1.9 nmol/L

Male aged 18-49 years: 8.3 - 30.2 nmol/L

Male aged >50 years: 7.7 - 24.8 nmol/L

 

Adults (mass spectrometry):

Female: <1.9 nmol/L

Male: 7.0-27.0 nmol/L

  

Paediatrics:

Group

Testosterone (nmol/L)

Neonates

Not reported (can be elevated during year 1)

Female Tanner 1

<0.6

Male Tanner 1

<0.7

 

Reference for mass spectrometry reference ranges: 

  • Kushnir et al (2010). Liquid Chromatography–Tandem Mass Spectrometry Assay for Androstenedione, Dehydroepiandrosterone, and Testosterone with Pediatric and Adult Reference Intervals. Clinical Chemistry 2010:56;1138–77.
  • Turnaround Time: 24 hours (immunoassay), 5 working days (mass spec)

Related Tests Follicle Stimulating Hormone (FSH) Luteinising Hormone (LH)

Theophylline

Theophylline

Reference Range

Therapeutic range: 10-20 mg/L (Pre-dose)

  • Minimum time for patient to reach steady state without loading or after dosage change is 2 days
  • Turnaround Time: 24 hours
Faecal Elastase-1

Faecal Elastase-1

Reference Range

Normal: >200 ug/g

Mild to moderate exocrine pancreatic insufficiency: 100 – 200 ug/g

Severe exocrine pancreatic insufficiency: <100 ug/g

  • Turnaround Time: 15 days
Adrenocorticotrophic Hormone (ACTH)

Adrenocorticotrophic Hormone (ACTH)

Reference Range

Provided by referral laboratory

  • Turnaround Time: 14 days

Related Tests Cortisol

Thiopurine S-Methyltransferase (TPMT)

Thiopurine S-Methyltransferase (TPMT)

Reference Range

 

TPMT phenotype/activity reference ranges:

  • <6 nmol/ghb/hr = Deficient
  • 6-34 nmol/gHb/hr = Low
  • 35-79 nmol/gHb/hr = Normal
  • >79 nmol/gHb/hr = High

TPMT genotype classifications:

  • WT = wild-type, normal result
  • H3 = TPMT 1*/3* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine.
  • H2 = TPMT 1*/2* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine
  • H03 = TPMT 3*/3* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • H02 = TPMT 2*/2* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • Turnaround Time: 14 days

Alanine Aminotransferase (ALT)

Reference Range

Adult male and female reference range: 0-55 IU/L (Abbott Alinity)

  • Turnaround Time: 24 hours

Related Tests Albumin Alkaline Phosphatase (ALP) Aspartate Aminotransferase (AST) Bilirubin (Direct) Bilirubin (Total) Gamma Glutamyl Transferase (GGT) Total Protein (serum)

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Protection of Personal Information – Clinical Laboratory Services comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

University Hospitals Birmingham medical laboratories at Queen Elizabeth Hospital, Heartlands Hospital, Good Hope Hospital and Solihull Hospital are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link: https://www.ukas.com/find-an-organisation/

  • Molecular Pathology is a UKAS accredited medical laboratory No. 8759
  • Biochemistry is a UKAS accredited medical laboratory No. 8910
  • Haematology and Transfusion is a UKAS accredited medical laboratory No. 8784
  • Clinical Microbiology is a UKAS accredited medical laboratory No. 8760
  • Cellular Pathology is a UKAS accredited medical laboratory No. 10141
  • Musculoskeletal laboratory is a UKAS accredited medical laboratory No. 9897
  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217.

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database: http://qehbpathology.uk/test-database

For further information contact Louise Fallon, Quality Manager, 0121 371 5962