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Biochemistry

Urine Osmolality

Urine Osmolality

Reference Range

None Given

  • Turnaround Time: 1 Day (Please contact the laboratory if urgent)
Urine pH

Urine pH

Reference Range

No reference range is reported for urine pH. Although urine pH normally ranges between 6.5 to 8.5 in healthy individuals, it varies with food consumption. Urine with a pH >6.0 is suggestive of alkali contamination or the presence of urea splitting bacteria. In a patient with metabolic acidosis, a urine pH >5.5 suggests a failure of urinary acidification which may indicate renal tubular acidosis.  

  • Turnaround Time:

    1 working day

Urine pH

Urine pH

Reference Range

No reference range is reported for urine pH. Although urine pH normally ranges between 6.5 to 8.5 in healthy individuals, it varies with food consumption. Urine with a pH >6.0 is suggestive of alkali contamination or the presence of urea splitting bacteria. In a patient with metabolic acidosis, a urine pH >5.5 suggests a failure of urinary acidification which may indicate renal tubular acidosis.  

  • Turnaround Time:

    1 working day

Urine Protein:Creatinine ratio (Random urine)

Reference Range

  • <15 mg/mmol Creatinine = Normal
  • 15 – 49 mg/mmol Creatinine = Trace Proteinuria. Consider ACEI or ARB in diabetes.
  • 50 – 99 mg/mmol Creatinine = Significant proteinuria. Repeat using early am sample. Consider ACEI or ARB in hypertension.
  • 100 – 300 mg/mmol Creatinine = High proteinuria. If new finding, seek nephrology advice regardless of eGFR.
  • >300 mg/mmol Creatinine = “Nephrotic range” proteinuria. If new finding, seek nephrology advice regardless of eGFR.
                                      
Proteinuria is a risk factor for cardiovascular disease and for decline in GFR in CKD
UK CKD Guidelines suggest if PCR is >100 mg/mmol patient should be referred to Nephrologists irrespective of GFR.
 

Source of Reference Range: NICE guideline CG73 (2008) and UK eCKD guidelines 2009.)

 

  • Turnaround Time: 1 Day
Vitamin B1 and Vitamin B6

Vitamin B1 and Vitamin B6

Reference Range

Vitamin B1: 66.5 to 200 nmol/L

Vitamin B6: 44 to 168 nmol/L

  • Turnaround Time: 2 to 3 weeks
Vitamin B12

Vitamin B12

Reference Range

<105 ng/L - B12 deficiency highly likely

105-200 ng/L - B12 deficiency possible (confirm with haematological/clinical findings)

>200 ng/L - B12 deficiency unlikely

*Note clinical advice is provided by Haematology

 

  • Turnaround Time: 1 day
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