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Haematology

Haematology Referred Work (11)

Bethesda / Inhibitor Assay (Human, Porcine and Bovine Chromogenic)

Bethesda / Inhibitor Assay (Human, Porcine and Bovine Chromogenic)

Reference Range

<0.6 BU/mL

  • Turnaround Time: 21 days
Emicizumab Assay

Emicizumab Assay

Reference Range

Therapeutic range: 40-60µg/ml

  • Turnaround Time: 21 days
Inhibitor Screen

Inhibitor Screen

Reference Range

<12% difference between incubated and immediate mix APTT

  • Turnaround Time: 21 days
Platelet Aggregation Test

Platelet Aggregation Test

  • Turnaround Time: 24 hours
Thrombophilia Screen (including lupus)

Thrombophilia Screen (including lupus)

Reference Range

Antithrombin function (AT) 83-127 IU/dL

Protein C function 65-171 IU/dL

Protein S Antigen (Free Protein S) Male: 75-139 IU/dL, Female: 55-125 IU/dL

Lupus Anticoagulant Screen - Please see report (reagent batch dependant)

Factor V Leiden mutation - Absent

Prothrombin gene 20210A mutation - Absent

  • Turnaround Time: 21 days
Direct Thrombin Inhibitor Assay (Argatroban and Dabigatran)

Direct Thrombin Inhibitor Assay (Argatroban and Dabigatran)

Reference Range

Argatroban: therapeutic range 0.4-1.2µg/m[1]

Dabigatran: target peak range 117-275 ng/ml for stroke prevention in NVAF and treatment of PE/VTE[1]

[1] Measurement of heparin, direct oral anti-coagulants and other non-coumarin anti-coagulants and their effects on haemostasis assays: A British Society for Haematology Guideline, Baker et al, Brit J Haematol, 2024.

 

 

  • Turnaround Time: 7 days (Unless urgent by prior arrangement with laboratory)
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