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Haematology

ADAMTS13 Activity / Inhibitor (IgG)

ADAMTS13 Activity / Inhibitor (IgG)

Reference Range

Reference Ranges are dependent upon methodology:

ADAMTS13 Activity:

ACUSTAR (primary method): 62-118 IU/dL

ELISA (secondary method, used for confirmatory check of equivocal results): 38-110%

ADAMTS13 inhibitor (IgG):

Neg <12 U/mL

Borderline 12-15 U/mL

Positive >15 U/mL

  • Turnaround Time: ADAMTS13 Activity: 6 hours for urgent requests, 7 days for routine requests, ADAMTS13 Inhibitor: 21 days.
Bethesda / Inhibitor Assay (Human and Porcine)

Bethesda / Inhibitor Assay (Human and Porcine)

Reference Range

<0.6 BU/mL

  • Turnaround Time: 21 days
Heparin Induced Thrombocytopenia Screen (HIT)

Heparin Induced Thrombocytopenia Screen (HIT)

Reference Range

Reference Ranges are dependent upon methodology:

ACUSTAR (primary method): 0-0.99 U/ml. HIT cannot be excluded for results => 1.0 U/ml

HIT ELISA (secondary method, used for VITT cases): >0.4-1.0 weak positive, >1.0 Positive

  • Turnaround Time: 21 days (Unless urgent by prior arrangement with laboratory)
Inhibitor Screen

Inhibitor Screen

Reference Range

<12% difference between incubated and immediate mix APTT

  • Turnaround Time: 21 days
Platelet Aggregation Test

Platelet Aggregation Test

  • Turnaround Time: 24 hours
PT / INR and Partial Thromboplastin Time (PTT)

PT / INR and Partial Thromboplastin Time (PTT)

Reference Range

Prothrombin Time ratio (PT) 0.8-1.2 (10-14.0 seconds)

INR Dependent upon therapeutic requirement

PTT Ratio 0.8-1.2 (23-34 seconds)

 

 

  • Turnaround Time: 24 hours
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