Biochemistry

Suitable Specimen Types

Serum

IGFBP-3 (Insulin-Like Growth Factor Binding Protein-3)

Specimen Volume

1 mL blood (250ul serum)

Sample Preparation

Centrifuge and separate serum and store at -20 ºC

Turnaround Time

4 weeks

Sample Processing In Laboratory

Usual

Sample Stability

36 days at 2 to 8C

General Information

Insulin-like growth factors circulate in complex with plasma binding proteins. Four major IGF-binding proteins have been described, but the main binding protein is IGFBP-3, which forms complexes with over 75% of the circulating IGF-1. The concentration of the binding protein is dependent upon growth hormone (GH) and can be used as a measure of IGF-1, and therefore GH, reserve.

Patient Preparation

None

Reference Range

Age and gender specific reference ranges, please contact laboratory

 

Specifications

  • EQA Status: UK NEQAS Guildford Peptide Hormones
  • EQAS Scheme: Yes

Related Tests

Growth Hormone (GH) IGF-1 (Insulin-like Growth Factor)

Creation Date

Monday, 08 August 2011

Modification Date

Thursday, 28 June 2018

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Copyright UHB Pathology 2018

Protection of Personal Information – Clinical Laboratory Services comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

University Hospitals Birmingham medical laboratories at Queen Elizabeth Hospital, Heartlands Hospital, Good Hope Hospital and Solihull Hospital are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link: https://www.ukas.com/find-an-organisation/

  • Molecular Pathology is a UKAS accredited medical laboratory No. 8759
  • Biochemistry is a UKAS accredited medical laboratory No. 8910
  • Haematology and Transfusion is a UKAS accredited medical laboratory No. 8784
  • Clinical Microbiology is a UKAS accredited medical laboratory No. 8760
  • Cellular Pathology is a UKAS accredited medical laboratory No. 10141
  • Musculoskeletal laboratory is a UKAS accredited medical laboratory No. 9897
  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217.

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database: http://qehbpathology.uk/test-database

For further information contact Louise Fallon, Quality Manager, 0121 371 5962