Preferred Sample Type

Argatroban

Argatroban

Specimen Volume

3.5 mL (Vacuette tubes) or 2.7mL (BD Vacutainer tubes)

Specimen Transport

Standard transport to laboratory

Sample Preparation

Samples must be filled to the black fill line (Vacuette tubes) or the frosted line (BD Vacutainer tubes) indicated on the sample tube. Any sample filled above or below this level will be rejected and a repeat sample will be required

Turnaround Time

7 days (Unless urgent by prior arrangement with laboratory)

Sample Processing In Laboratory

Sample should be centrifuged

Sample Stability

12 hours from venepuncture (ideally received no later than 4 hours after collection)

General Information

Test Availability:

Queen Elizabeth only

 Samples received at other sites will be sent on to the Queen Elizabeth Laboratory.

Samples that meet the following criteria will not be processed:

  • Haemolysed, clotted, underfilled or overfilled samples.
  • Samples >12 hours old from the time of collection.
  • Samples received from other hospital laboratories that have been frozen and thawed.
  • Samples which fail the minimum data set.

Assay Limitations:

No interferences up to:

Haemoglobin: 1000 mg/dl

Triglycerides: 875 mg/dl

Bilirubin (Free): 60 mg/dl         

Bilirubin (Conjugated): 60 mg/dl        

Apixaban: 100 ng/dl

In addition, the reagent does not contain heparin inhibitors, therefore interference by edoxaban, rivaroxaban and heparins on assay results could be shown.

Reference Range

The therapeutic range for the argatroban assay is 0.4-1.2µg/ml

Specifications

  • EQA Status: ECAT
  • EQAS Scheme: Yes

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