It is mandatory that serious transfusion hazards and incidents must be recognised, managed and reported to either SHOT (Serious Hazards of Transfusion); and/or SABRE (Serious Adverse Blood Reactions and Events). All blood transfusion related incidents, including serious transfusion reactions, must be reported using the Trust Clinical Incident process. In addition Blood Bank must be notified immediately by telephone so that appropriate investigation can be undertaken which may include the immediate withdrawal of issued components. The Hospital Transfusion Team will generate a report for SHOT and SABRE, and the matter will be reported to the Hospital Transfusion Committee. All transfusion reactions will be investigated by the laboratory.