Preferred Sample Type

Issuing FFP/Cryoprecipitate/Octaplas

Suitable Specimen Types

EDTA Whole Blood

Issuing FFP/Cryoprecipitate/Octaplas

Specimen Volume

4mL

Specimen Transport

Standard transport to laboratory.

Sample Preparation

Please refer to the trust guidelines on sample collection and labelling.

Sample Processing In Laboratory

Sample should be centrifuged

Sample Stability

Up to 7 days depending on patients transfusion history.

Notes

Coagulation factors can be preserved in plasma frozen soon after collection and stored at or below -25°c. In that state fresh frozen plasma (FFP) and cryoprecipitate can be kept frozen for up to 3 years. The products are usually used to prevent or stop bleeding due to deficiencies of coagulation factors which may be brought about in various ways.

Indications for transfusion are as follows:
FFP:
• Major Haemorrhage
• Bleeding INR > 1.5, APTR >1.5
• Pre op INR >1.5, APTR >1.5
• Liver Impairment and pre op INR >2.0
• TEG/ROTEM Indicated

Cryoprecipitate:
• Major Haemorrhage
• Bleeding Fibrinogen <1.5g/l
• Pre op Fibrinogen <1.0g/l
• TEG/ROTEM Indicated

Prior to the issuing of Blood and Blood components patients are required to have had their blood group tested / confirmed on samples taken at two separate venepunctures. If this has not been carried out then group AB or A HT negative components can be thawed in emergency situations.

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