Preferred Sample Type
Suitable Specimen Types
SerumOestradiol
Specimen Volume
2 mL bloodSample Preparation
Centrifuge
Turnaround Time
1 DaySample Processing In Laboratory
Usual
Sample Stability
2 days at 4 'C
General Information
Oestrogens are responsible for the development of secondary female sex characteristics and are involved in the control of the female reproductive process.
Oestradiol levels are used to evaluate ovarian function and to help diagnose the cause of precocious puberty in girls (very early signs of puberty) and gynaecomastia in men. Its main use has been to help diagnose the reason for amenorrhoea (for example, to determine whether the cause is menopause, pregnancy, or a medical problem). In treatment of sub-fertility, repeated measurements are used to follow follicle development in the ovary in the days prior to in-vitro fertilisation. Oestradiol may also be used to monitor menopausal hormone replacement therapy, if given as 17-oestradiol by implant.
Patient Preparation
None
Notes
None Given
Reference Range
Female:
- Follicular: 77 - 921 pmol/L
- Mid-cycle: 140 - 2383 pmol/L
- Luteal: 77 - 1145 pmol/L
- Post menopausal: <37 - 103 pmol/L
Male:
- 40 - 162 pmol/L
Specifications
- EQA Status: NEQAS
- EQAS Scheme: Yes