Preferred Sample Type
Glucose (CSF)
Specimen Volume
5-10 mL vacutainer (minimum sample volume 50 uL)Sample Preparation
Analysis should be undertaken promptly because glucose metabolism continues after the sample has been aspirated.
Turnaround Time
1 daySample Processing In Laboratory
Usual
Sample Stability
If unable to analyse sample immediately, store at 4 ºC.
General Information
CSF glucose or glycorrhachia is a measurement used to determine the levels of glucose in cerebrospinal fluid. Normal levels are about 2/3 the concentration of blood glucose. Glucose levels may decrease when cells that are not normally present metabolise the glucose. These may include bacteria or cells present due to inflammation (WBCs) or shed by tumours. CSF glucose will therefore be decreased in bacterial meningitis, tuberculous meningitis and subarachnoid haemorrhage. Glucose levels are usually within normal limits in viral or aseptic meningitis.
Patient Preparation
None
Notes
None Given
Reference Range
Adults: 2.2 - 3.9 mmol/L
Results should be interpreted in relation to concurrent plasma values (the CSF glucose concentration should be 60% of the plasma glucose concentration).
Specifications
-
EQA Status:
Neqas
- EQAS Scheme: Yes