Suitable Specimen Types
Tissue TissueMGMT Promoter Methylation (Therascreen Methylation Sequencing)
General Information
ACCREDITATION STATUS: ACCREDITED
Turnaround Time
>90% in 7-10 days
Mutation Spectrum
IDH1 codons: 100, 132
IDH2 codon: 172
Specimen Requirements
- Paraffin block from biopsy, resection or cell block
- 4-6μm on uncharged slides
Please note tissue handling, tissue fixation, time between cutting and staining and excessive drying can lead to loss of expression. Fixatives containing alcohol should not be used and use of Bouin’s fixative will preclude testing by FISH methods.
A copy of the original Pathology report where possible.