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Molecular Pathology - TATs

Molecular Pathology Diagnostic Service

Turnaround Time & Test Repertoire

MPDS offers a range of molecular tests across a wide range of cancer types. A detailed list of tests, technologies and turnaround times can be found in the document below.

Document

Test repertoire & TATs 2025/26

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Service users are advised to contact the service directly where a shorter turnaround time is essential for patient management, or where a report has not reached them within the stated turnaround time.

Tumour types tested (not exhaustive)

Lung non-small cell carcinoma
Head & neck carcinoma
Thyroid carcinoma
Breast carcinoma
Cholangiocarcinoma
Gastric / oesophageal carcinoma
Colorectal carcinoma
Urothelial carcinoma
Prostatic adenocarcinoma
Cervical carcinoma
Endometrial carcinoma
Carcinomas of unknown primary
Melanoma
GIST
Soft tissue sarcoma
Central nervous system (CNS) tumours
Lymphoma

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Molecular Pathology - Return of Material

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Guidance from The Royal College of Pathologists and Institute of Biomedical Science recommends residual DNA remaining following completion of testing is stored for a minimum of 8 weeks. Current storage capacity allows retention of DNA for a minimum period of 3 years. Referred specimens (blocks/ unused slides) will be retained for 2 weeks after testing is complete before being returned to the referring pathology. Material is returned using sample tracking and confirmation of receipt is requested. If a specimen is required prior to test completion or within a specified time frame this should be clearly communicated to the service.

If you require the urgent return of material, please click the link below.

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Molecular Pathology Request Forms

All external users should complete the external request form. We ask that the forms are completed in full and if handwritten, in block capitals so that the form is legible. Missing information could lead to a delay in testing as some information is vital in order for a case to be booked in. 

Please find and download the relevant request forms below. Please contact  the Molecular Specimen Reception on 0121 371 3325 or This email address is being protected from spambots. You need JavaScript enabled to view it. with any queries regarding the request forms.

Lung Cancer Testing
including EGFR, ALK, PD-L1 & ROS


Lung Cancer Request Form

EGFR Mutation Testing on Circulating Tumour DNA


EGFR Circulating Tumour DNA Request Form

Colorectal Cancer Testing
including KRAS, NRAS, BRAF, MMR IHC & MLH-1 
Colorectal Cancer Request Form
GIST Testing
including KIT & PDGFRA and BRAF 
GIST Testing Request Form
PD-L1 Lung Cancer Testing Prior to Pembrolizumab Therapy
including PD-L1 22C3 IHC
PD-L1 Lung Cancer Request Form
PD-L1 Bladder Cancer Testing Prior to Pembrolizumab or Atezolizumab Therapy
including PD-L1 22C3 IHC & PD-L1 SP142 IHC
PD-L1 Bladder Cancer Request Form
PD-L1 Breast Cancer Testing
PD-L1 Breast Cancer Request Form 
Melanoma Testing
including BRAF, NRAS, KIT and PD-L1 28-8 
Melanoma Testing Request Form 
Breast and Gastric Cancer Testing
including IHC & FISH 
Breast and Gastric Cancer Request Form 
Neuropathology Molecular Testing
Molecular Neuropathology Testing Request Form 
Thyroid Cancer Molecular Testing
including IHC & PCR 
Thyroid Cancer Testing Request Form 
PD-L1 Head & Neck Cancer Testing
including 28-8 & 22c3 
Head & Neck PD-L1 Request Form 

 

Molecular Pathology - Request a Test

 

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Molecular - Contact us

Molecular Pathology Diagnostic Service

Contact us

For general enquiries, please contact Specimen Reception.

Clinical service lead

Dr Philippe Taniere

CSL - Molecular Pathology / Consultant Histopathologist

Phone

0121 371 3325 (ext. 13325)

Email

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Emails with patient identifiable data must only be sent using nhs.net addresses.

Deputy clinical service lead

Brendan O'Sullivan

Phone

0121 371 3325 (ext. 13325)

Email

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Emails with patient identifiable data must only be sent using nhs.net addresses.

Principal clinical scientist

Nicola Chadderton

Phone

0121 371 3989 (ext. 13989)

Email

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Emails with patient identifiable data must only be sent using nhs.net addresses.

Principal clinical scientist

Lisa James

Phone

0121 371 3990 (ext. 13990)

Email

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Emails with patient identifiable data must only be sent using nhs.net addresses.

Specimen reception

Contact the lab

Contact us for general enquiries, test updates, or to request PAXgene ccfDNA tube stock. If asking about a case, have the patient's full name and date of birth ready.

Phone

0121 371 3325 (ext. 13325)

Email

This email address is being protected from spambots. You need JavaScript enabled to view it.
Emails with patient identifiable data must only be sent using nhs.net addresses.

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Specimens

Blood

In general the following blood collection bottles are required (colour reference is Greiner Vacuette® system only, other systems may vary). The collection tube required by test is given in section 5.9. Please contact the laboratory if you are unsure of the correct collection tube.

Urine Collections

Bottles for 24 hour urine collections can be obtained from the Clinical Biochemistry Department. Different preservatives are required for different analyses. Please ensure that ward staff/portering staff/patients who are sent to collect containers know which analyses will be required. Please ensure that patient information on the specimen bottles is complete before they are returned to the laboratory.

Add-on Tests

  • QEHB inpatients and outpatients: Please send a request form with the patient’s details and tests required, clearly stating it is an add-on request.
  • Moseley Hall Hospital, St Mary’s Hospice, Royal Orthopaedic Hospital and GP surgeries: Please telephone extension 16543 to request additional tests.

Please note that add-on tests will not be dealt with urgently. Due to sample storage procedures within the department, it may not be possible to access a sample quickly, if an add-on result is required urgently, it may be more appropriate to re-bleed the patient.

Please be aware that due to varying in vitro stability of analytes, it may not be possible to add-on further tests.

Please call extension 16543 to discuss if required.

Specific Analyses

The Department of Clinical Biochemistry performs the majority of routine assays in-house. A small number of specialist assays are forwarded on to centres elsewhere in the UK although advice and interpretation will always be available locally.

The Department of Clinical Biochemistry has particular expertise in; the investigation of diabetes mellitus, lipid disorders, gastroenterology, rheumatology, tumour markers and endocrinology. An extensive analytical service is provided within the Diabetes Centre.

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