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Categories starting with T

Toxicology (1)

Items starting with T

Tacrolimus (FK506 or Prograf)

Tacrolimus (FK506 or Prograf)

Reference Range

Reference or therapeutic ranges are not reported as therapeutic target ranges are applied on an individual basis dependent upon specialty, dosing, period in treatment regime and clinical status. Further advice can be obtained from the appropriate speciality.

  • Turnaround Time: 24 hours

Related Tests Cyclosporin (Ciclosporine) Everolimus Sirolimus (aka Rapamycin or Rapamune)

Testosterone

Testosterone

Reference Range

Adults (mass spectrometry):

Female: <1.9 nmol/L

Male: 7.0-27.0 nmol/L

 

Adult males (Alinity IA):

7.7-24.8 nmol/L

 

Paediatrics:

Group

Testosterone

(nmol/L)

Neonates

Not reported (can be elevated during year 1)

Female Tanner 1

<0.6

Male Tanner 1

<0.7
  • Turnaround Time: 72 hours (MS), 24 hours (IA)

Related Tests Follicle Stimulating Hormone (FSH) Luteinising Hormone (LH)

Theophylline

Theophylline

Reference Range

Therapeutic range: 10-20 mg/L (Pre-dose)

  • Minimum time for patient to reach steady state without loading or after dosage change is 2 days
  • Turnaround Time: 24 hours
Thiopurine S-Methyltransferase (TPMT)

Thiopurine S-Methyltransferase (TPMT)

Reference Range

 

TPMT phenotype/activity reference ranges:

  • <6 nmol/ghb/hr = Deficient
  • 6-34 nmol/gHb/hr = Low
  • 35-79 nmol/gHb/hr = Normal
  • >79 nmol/gHb/hr = High

TPMT genotype classifications:

  • WT = wild-type, normal result
  • H3 = TPMT 1*/3* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine.
  • H2 = TPMT 1*/2* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine
  • H03 = TPMT 3*/3* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • H02 = TPMT 2*/2* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • Turnaround Time: 14 days
Thrombin Time

Thrombin Time

Reference Range

0.8-1.2

  • Turnaround Time: 24 hours
Thrombophilia Screen

Thrombophilia Screen

Reference Range

Antithrombin function (AT) 83-127 u/dL

Protein C function 65-171 u/dL

Protein S Antigen (Free Protein S) Male: 75-139 u/dL, Female: 55-125 u/dL

Lupus Anticoagulant Screen - Please see report (reagent batch dependant)

Factor V Leiden mutation - Absent

Prothrombin gene 20210A mutation - Absent

  • Turnaround Time: 21 days
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Protection of Personal Information – Clinical Laboratory Services comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

University Hospitals Birmingham medical laboratories at Queen Elizabeth Hospital, Heartlands Hospital, Good Hope Hospital and Solihull Hospital are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link: https://www.ukas.com/find-an-organisation/

  • Molecular Pathology is a UKAS accredited medical laboratory No. 8759
  • Biochemistry is a UKAS accredited medical laboratory No. 8910
  • Haematology and Transfusion is a UKAS accredited medical laboratory No. 8784
  • Clinical Microbiology is a UKAS accredited medical laboratory No. 8760
  • Cellular Pathology is a UKAS accredited medical laboratory No. 10141
  • Musculoskeletal laboratory is a UKAS accredited medical laboratory No. 9897
  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217.

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database: http://qehbpathology.uk/test-database

For further information contact Louise Fallon, Quality Manager, 0121 371 5962