a b c d e f g h i j k l m n o p q r s t u v w x y z #

Categories starting with T

Toxicology (2)

Items starting with T

Testosterone

Testosterone

Reference Range

Adults:

Female: <1.9 nmol/L

Male: 7.0-27.0 nmol/L

Paediatrics:

Female Tanner stage 1: <0.6 nmol/L

Male Tanner stage 1: <0.7 nmol/L

  • Turnaround Time: 72 hours

Related Tests Follicle Stimulating Hormone (FSH) Luteinising Hormone (LH)

Theophylline

Theophylline

Reference Range

Therapeutic range: 10-20 mg/L (Pre-dose)

  • Minimum time for patient to reach steady state without loading or after dosage change is 2 days
  • Turnaround Time: 24 hours
Thiopurine S-Methyltransferase (TPMT)

Thiopurine S-Methyltransferase (TPMT)

Reference Range

 

TPMT phenotype/activity reference ranges:

  • <6 nmol/ghb/hr = Deficient
  • 6-34 nmol/gHb/hr = Low
  • 35-79 nmol/gHb/hr = Normal
  • >79 nmol/gHb/hr = High

TPMT genotype classifications:

  • WT = wild-type, normal result
  • H3 = TPMT 1*/3* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine.
  • H2 = TPMT 1*/2* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine
  • H03 = TPMT 3*/3* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • H02 = TPMT 2*/2* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • Turnaround Time: 14 days
Thrombin Time

Thrombin Time

Reference Range

0.8-1.2

  • Turnaround Time: 24 hours
Thrombophilia Screen

Thrombophilia Screen

Reference Range

Antithrombin function (AT) 83-127 u/dL

Protein C function 65-171 u/dL

Protein S Antigen (Free Protein S) Male: 75-139 u/dL, Female: 55-125 u/dL

Lupus Anticoagulant Screen - Please see report (reagent batch dependant)

Factor V Leiden mutation - Absent

Prothrombin gene 20210A mutation - Absent

  • Turnaround Time: 21 days

Thyroglobulin

Reference Range

No reference ranges applicable. Results must be interpreted with Tg antibodies. Tg analysis is most sensitive when TSH is not suppressed (>30 mIU/L) i.e. any small thyroid remnants of disease present should produce measurable Tg

Elevations in Tg post-thyroidectomy for differentiated thyroid cancer can indicate recurrence of disease or metastasis

Interpretation of results also depends on factors such as whether the patient is on T4/T3 replacement.

The limit of detection of the assay is < 5 ug/L.

Higher levels may be seen in the newborn and in the third trimester of pregnancy.

Benign elevations:

  • Grave's
  • Hashimoto's
  • Adenoma

References

British Thyroid Association & Royal College of Physicians, Thyroid Cancer Guidelines 2007

Spencer et al., 2005. Clinical Impact of Tg and TgAb Method Differences on the Management of Patients with Differentiated Thyroid Carcinomas. J Clin Endocrinol Metab 90:5566-5575

   

 

  • Turnaround Time: 10 days

Related Tests Free T4 (FT4) Thyroxine Free Triodothyronine (FT3) Thyrotrophin (TSH)

[1] 2 3  >>  

General Information

General information about the website and its content

Read more

Location of Laboratories

Where the laboratories are located and information about the services offered at each laboratory

Read more

Copyright UHB Pathology 2018

Protection of Personal Information – Clinical Laboratory Services comply with the Trust Data Protection Policy and have procedures in place to allow the Directorate and it’s employees to comply with the Data Protection Act 1998 and associated best practice and guidance.

The Trust Laboratories at Heartlands Hospital, University Hospitals Birmingham, Good Hope Hospital and Solihull Hospital were all hold UKAS (United Kingdom Accreditation Service) accreditation to the internationally recognised ISO 15189 standard For a list of accredited tests and other information please visit the UKAS website. For further test information please visit the test database:

http://qehbpathology.uk/test-database

Tests not appearing on appearing on the UKAS scope,  are either under consideration or in the process of accreditation and so currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further information contact Louise Fallon, Quality Manager, 0121 371 5962