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Categories starting with T

Items starting with T

Tacrolimus (FK506 or Prograf)

Tacrolimus (FK506 or Prograf)

Reference Range

Reference or therapeutic ranges are not reported as therapeutic target ranges are applied on an individual basis dependent upon specialty, dosing, period in treatment regime and clinical status. Further advice can be obtained from the appropriate speciality.

  • Turnaround Time: 24 hours
Testosterone

Testosterone

Reference Range

Adults (mass spectrometry):

Female: <1.9 nmol/L

Male: 7.0-27.0 nmol/L

 

Adult males (Alinity IA):

7.7-24.8 nmol/L

 

Paediatrics:

Group

Testosterone

(nmol/L)

Neonates

Not reported (can be elevated during year 1)

Female Tanner 1

<0.6

Male Tanner 1

<0.7

  • Turnaround Time: 72 hours (MS), 24 hours (IA)
Theophylline

Theophylline

Reference Range

Therapeutic range: 10-20 mg/L (Pre-dose)

  • Minimum time for patient to reach steady state without loading or after dosage change is 2 days
  • Turnaround Time: 24 hours
Thiopurine S-Methyltransferase (TPMT)

Thiopurine S-Methyltransferase (TPMT)

Reference Range

 

TPMT phenotype/activity reference ranges:

  • <6 nmol/ghb/hr = Deficient
  • 6-34 nmol/gHb/hr = Low
  • 35-79 nmol/gHb/hr = Normal
  • >79 nmol/gHb/hr = High

TPMT genotype classifications:

  • WT = wild-type, normal result
  • H3 = TPMT 1*/3* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine.
  • H2 = TPMT 1*/2* - heterozygous for TPMT, this would indicate a reduced activity.  Advise reduce dose of azothioprine
  • H03 = TPMT 3*/3* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • H02 = TPMT 2*/2* - homozygous for TPMT, this would indicated deficient TPMT activity.  Advise stop treatment with azothioprine.
  • Turnaround Time: 14 days
Thrombin Time

Thrombin Time

Reference Range

0.8-1.2

  • Turnaround Time: 24 hours
Thrombophilia Screen

Thrombophilia Screen

Reference Range

Antithrombin function (AT) 83-127 u/dL

Protein C function 65-171 u/dL

Protein S Antigen (Free Protein S) Male: 75-139 u/dL, Female: 55-125 u/dL

Lupus Anticoagulant Screen - Please see report (reagent batch dependant)

Factor V Leiden mutation - Absent

Prothrombin gene 20210A mutation - Absent

  • Turnaround Time: 21 days
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