Preferred Sample Type


Suitable Specimen Types



Specimen Volume

2 mL blood

Sample Preparation


Turnaround Time

1 Day

Sample Processing In Laboratory


Sample Stability

2 days at 4 'C

General Information

Oestrogens are responsible for the development of secondary female sex characteristics and are involved in the control of the female reproductive process.

Oestradiol levels are used to evaluate ovarian function and to help diagnose the cause of precocious puberty in girls (very early signs of puberty) and gynaecomastia in men. Its main use has been to help diagnose the reason for amenorrhoea (for example, to determine whether the cause is menopause, pregnancy, or a medical problem). In treatment of sub-fertility, repeated measurements are used to follow follicle development in the ovary in the days prior to in-vitro fertilisation. Oestradiol may also be used to monitor menopausal hormone replacement therapy, if given as 17-oestradiol by implant.

Patient Preparation



None Given

Reference Range


    • Follicular:               77 -   921   pmol/L
    • Mid-cycle:              140 - 2383  pmol/L
    • Luteal:                    77 - 1145  pmol/L
    • Post menopausal:   <37 - 103   pmol/L


    • 40 - 162  pmol/L


  • EQA Status: NEQAS
  • EQAS Scheme: Yes

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